Start » Arbeitsgruppe Translationale Kardiologie

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  1. Prof. Ntziachristos, Institut für biologische und Medizinische Bildgebung am Helmholtz Zentrum München, Technische Universität München
  2. Prof. Weichert, Institut für Pathologie, Technische Universität München
  3. Prof. Renu Virmani, CVPath Institute, Gaithersburg, USA
  4. Prof. Alexiou, Institute für Nanotechnologie (SEON), Universität Erlangen
  1. DZHK translational research project: “Detection of plaque vulnerability with a novel hybrid intravascular NIRF-IVUS imaging system”
  2. Leducq PlaqOmics Network: “Defining the Roles of Smooth Muscle Cells and Other Extracellular Matrix Producing Cells in Late Stage Atherosclerotic Plaque Pathogenesis”
  3. European Society of Cardiology (ESC), grants for “Medical Research Innovation”. Systemic vs. Site Targeted Treatment of Neoatherosclerosis
  4. EU FP7-HEALTH-2010-single-stage: PRESTIGE (PREvention of late Stent Thrombosis by an Interdisciplinary Global European effort).
  5. IGGSE: “Differential Integrin Activation in the Process of Restenosis and Endothelialization of Human Stents”
  6. KKF “Differentielle Integrinaktivierung im Restenose – und Reendothelialisierungsprozess humaner Stentimplantate”
  7. BIOTRONIK SE & Co. KG: Preclinical evaluation of the biodegradable magnesium stent
  8. BIOTRONIK SE & Co. KG: ISAR-ORSIRO-OCT study
  9. Medtronic: ISAR-ZES/EES-OCT study
  1. Joner M ,.., Virmani R. Pioglitazone inhibits in-stent restenosis in atherosclerotic rabbits by targeting transforming growth factor-beta and mcp-1. Arterioscler Thromb Vasc Biol. 2007
  2. Joner M ,.., Virmani R. Site-specific targeting of nanoparticle prednisolone reduces in-stent restenosis in a rabbit model of established atheroma. Arterioscler Thromb Vasc Biol. 2008
  3. Otsuka F ,.., Joner M. Neoatherosclerosis: overview of histopathologic findings and implications for intravascular imaging assessment. Eur Heart J. 2015
  4. Joner M ,.., Virmani R. Endothelial cell recovery between comparator polymer-based drug-eluting stents. J Am Coll Cardiol. 2008
  5. Joner M ,.., Virmani R. Pathology of drug-eluting stents in humans: delayed healing and late thrombotic risk. J Am Coll Cardiol. 2006
  6. Virmani R ,.., Joner M. Matching human pathology is essential for validating OCT imaging to detect high-risk plaques. Nat Rev Cardiol. 2014
  7. Otsuka F, Joner M ,.., Narula J. Clinical classification of plaque morphology in coronary disease. Nat Rev Cardiol. 2014
  8. Yahagi K ,.., Joner M. Neoatherosclerosis: mirage of an ancient illness or genuine disease condition? Eur Heart J. 2015
  9. Yahagi K ,.., Joner M, Virmani R. Multiple simultaneous plaque erosion in 3 coronary arteries. JACC Cardiovasc Imaging. 2014
  10. Virmani R, Joner M, Sakakura K. Recent highlights of ATVB: calcification. Arterioscler Thromb Vasc Biol. 2014
  11. Yahagi K ,.., Joner M. Pathophysiology of superficial femoral artery in-stent restenosis. J Cardiovasc Surg (Torino). 2014
  12. Otsuka F ,.., Joner M, Virmani R. Natural progression of atherosclerosis from pathologic intimal thickening to late fibroatheroma in human coronary arteries: A pathology study. Atherosclerosis. 2015
  13. Otsuka F ,.., Joner M, Virmani R. Has our understanding of calcification in human coronary atherosclerosis progressed? Arterioscler Thromb Vasc Biol. 2014
  14. Malle C ,.., Joner M. Tissue characterization after drug-eluting stent implantation using optical coherence tomography. Arterioscler Thromb Vasc Biol. 2013
  15. Joner M, Giacoppo D, Kastrati A. Molecular multimodality imaging: has a long-standing dream come true? Eur Heart J. 2016
  16. Joner M, ….Kastrati A. Neoatherosclerosis in Patients With Coronary Stent Thrombosis: Findings From Optical Coherence Tomography Imaging (A Report of the PRESTIGE Consortium). JACC: Cardiovascular Interventions 2018
  17. Nicol P,…Joner M. Validation and application of OCT tissue attenuation index for the detection of neointimal foam cells. International Journal of Cardiovascular Imaging 2020
  18. Nicol P…Joner M. Assessment of a pro-healing stent in an animal model of early neoatherosclerosis. Scientific Reports 2020
  19. Nicol P…Joner M. Preclinical investigation of neoatherosclerosis in magnesium-based bioresorbable scaffolds versus thick-strut drug-eluting stents. Eurointervention 2020