*Krane M, *Dreßen M, *Santamaria G, *My I, *Schneider CM, *Dorn T, *Laue S, Mastantuono E, Berutti R, Rawat H, Gilsbach R, Schneider P, Lahm H, Schwarz S, Doppler SA, Paige S, Puluca N, Doll S, Neb I, Brade T, Zhang Z, Abou-Ajram C, Northoff B, Holdt LM, Sudhop S, Sahara M, Goedel A, Dendorfer A, Tjong FVY, Rijlaarsdam ME, Cleuziou J, Lang N, Kupatt C, Bezzina C, Lange R, Bowles NE, Mann M, Gelb BD, Crotti L, Hein L, Meitinger T, Wu S, Sinnecker D, Gruber PJ, Laugwitz KL, Moretti A. Sequential Defects in Cardiac Lineage Commitment and Maturation Cause Hypoplastic Left Heart Syndrome. Circulation. 2021 Oct 26;144(17):1409-1428. doi: 10.1161/CIRCULATIONAHA.121.056198. Epub 2021 Oct 25. PMID: 34694888; PMCID: PMC8542085.
König KC, Lahm H, Dreßen M, Doppler SA, Eichhorn S, Beck N, Kraehschuetz K, Doll S, Holdenrieder S, Kastrati A, Lange R and Krane M. Aggrecan: a new biomarker for acute type A aortic dissection. Sci Rep. 2021;11:10371. doi: 10.1038/s41598-021-89653-y. PMID: 33990642
Neiburga KD, Vilne B, Bauer S, Bongiovanni D, Ziegler T, Lachmann M, Wengert S, Hawe JS, Güldener U, Westerlund AM, Li L, Pang S, Yang C, Saar K, Huebner N, Maegdefessel L, DigiMed Bayern Consortium, Lange R, Krane M, Schunkert H, von Scheidt M. Vascular Tissue Specific miRNA Profiles Reveal Novel Correlations with Risk Factors in Coronary Artery Disease. Biomolecules. 2021 Nov 12;11(11):1683. doi: 10.3390/biom11111683. PMID: 34827683; PMCID: PMC8615466.
Lahm H, Jia M, Dreßen M, Wirth F, Puluca N, Gilsbach R, Keavney BD, Cleuziou, J, Beck N, Bondareva O, Dzilic E, Burri M, König KC, Ziegelmüller JA, Abou-Ajram, C, Neb I, Zhang Z, Doppler SA, Mastantuono E, Lichtner P, Eckstein G, Hörer J, Ewert P, Priest JR, Hein L, Lange R, Meitinger T, Cordell HJ, Müller-Myhsok B, Krane M.
Congenital heart disease risk loci identified by genome-wide association study in European patients.
J Clin Invest. 2021 Jan19;131(2):e141837.
https://pubmed.ncbi.nlm.nih.gov/33201861/
Krane M, Boehm J, Prinzing A, Ziegelmueller J, Holfeld J, Lange R.
Excellent Hemodynamic Performance After Aortic Valve Neocuspidization Using Autologous Pericardium.
Ann Thorac Surg. 2021 Jan;111(1):126-133.
https://pubmed.ncbi.nlm.nih.gov/32540439/
Lange R, Vitanova K.
Low-Flow, Low-Gradient Severe Aortic Stenosis: Are We Aware of the Perfect Treatment Option?
JACC Cardiovasc Interv. 2021 Jul 12;14(13):1493-1494.
https://pubmed.ncbi.nlm.nih.gov/34238559/
Ruge H, Burri M, Erlebach M, Lange R.
Access site related vascular complications with third generation transcatheter heart valve systems.
Catheter Cardiovasc Interv. 2021 Feb 1;97(2):325-332.
https://pubmed.ncbi.nlm.nih.gov/32588968/
Krane M, Wirth F, Boehm J, Lange R.
Do we need to rethink treatment of aortic valve pathologies in younger patients?
Eur J Cardiothorac Surg. 2021 Jul 14;60(1):46-47.
https://pubmed.ncbi.nlm.nih.gov/33899098/
König KC, Lahm H, Dreßen M, Doppler SA, Eichhorn S, Beck N, Kraehschuetz K, Doll S, Holdenrieder S, Kastrati A, Lange R, Krane M. Aggrecan: a new biomarker for acute type A aortic dissection.
Sci Rep. 2021 May 14;11(1):10371.
https://pubmed.ncbi.nlm.nih.gov/33990642/
Hesse M, Bednarz R, Carls E, Becker C, Bondareva O, Lother A, Geisen C,
Dreßen M, Krane M, Roell W, Hein L, Fleischmann BK, Gilsbach R.
Proximity to injury, but neither number of nuclei nor ploidy define pathological adaptation and plasticity in cardiomyocytes.
J Mol Cell Cardiol. 2021 Mar;152:95-104.
https://pubmed.ncbi.nlm.nih.gov/33290769/
Voss S, Ernst A, Erlebach M, Ruge H, Sideris K, Bleiziffer S, Voss B,
Tassani-Prell P, Mayr NP.
Effects of a dual-filter-based cerebral embolic protection device in transcatheter aortic valve replacement on cerebral oxygen saturation: A prospective pilot study.
J Card Surg. 2021 Apr;36(4):1241-1248.
https://pubmed.ncbi.nlm.nih.gov/33484180/
Mayr B, Burri M, Strbad M, Cleuziou J, Hager A, Ewert P, Hörer J, Lange R,
Ono M.
Common atrioventricular valve surgery in children with functional single
ventricle.
Eur J Cardiothorac Surg. 2021 May 19:ezab220.
https://pubmed.ncbi.nlm.nih.gov/34008032/
Ruge H, Xhepa E, Joner M, König C, Ried T, Imeri E, Herold U, Krane M, Lange R, Erlebach M.
First-in-Man Simultaneous Aortic and Mitral Valve Transcatheter
Implantation Using Patient-Customized Prostheses.
JACC Case Rep. 2021 Apr 21;3(4):653-657.
https://pubmed.ncbi.nlm.nih.gov/34317597/
Cleuziou J, Huber AK, Strbad M, Ono M, Hager A, Hörer J, Lange R.
Factors Affecting Health-Related Quality of Life After the Arterial Switch Operation.
World J Pediatr Congenit Heart Surg. 2021 May;12(3):344-351.
https://pubmed.ncbi.nlm.nih.gov/33942696/
Erlebach M, Ruge H, Lange R.
Transcatheter Aortic Valve Replacement for a Degenerated Transcatheter Valve-A Single Center Experience.
Thorac Cardiovasc Surg. 2021 Feb 24.
https://pubmed.ncbi.nlm.nih.gov/33626590/
Sideris K, Burri M, Prinzing A, Voss S, Krane M, Guenzinger R, Lange R, Voss
Mitral valve repair with the edge-to-edge technique: A 20 years single-center
experience.
J Card Surg. 2021 Apr;36(4):1298-1304.
https://pubmed.ncbi.nlm.nih.gov/33512725/
Chirikian O, Goodyer WR, Dzilic E, Serpooshan V, Buikema JW, McKeithan W, Wu H, Li G, Lee S, Merk M, Galdos F, Beck A, Ribeiro AJS, Paige S, Mercola M, Wu JC, Pruitt BL, Wu SM.
CRISPR/Cas9-based targeting of fluorescent reporters to human iPSCs to isolate atrial and ventricular-specific cardiomyocytes.
Sci Rep. 2021 Feb 4;11(1):3026.
https://pubmed.ncbi.nlm.nih.gov/33542270/
Voss S, Campanella C, Burri M, Trenkwalder T, Sideris K, Erlebach M, Ruge H, Krane M, Vitanova K, Lange R.
Anatomical reasons for failure of dual-filter cerebral embolic protection application in TAVR: A CT-based analysis.
J Card Surg. 2021 Sep 27.
https://pubmed.ncbi.nlm.nih.gov/34580919/
Deutsch O, Deisenhofer I, Koch-Buettner K, Lange R, Krane M.
Need for permanent pacemaker implantation following implantation of the rapid deployment valve in combined procedures: a single centre cohort study. J Thorac Dis. 2021 Apr;13(4):2128-2136.
https://pubmed.ncbi.nlm.nih.gov/34012563/
Burri M, Ruge H, Erlebach M, Lange R.
Surgical Cutdown Avoids Vascular Complications in Transcatheter Aortic Valve Replacement in Calcified and Small Femoral Arteries.
Thorac Cardiovasc Surg. 2021 Mar 24.
https://pubmed.ncbi.nlm.nih.gov/33761568/
Querdel E, Reinsch M, Castro L, Köse D, Bähr A, Reich S, Geertz B, Ulmer B,
Schulze M, Lemoine MD, Krause T, Lemme M, Sani J, Shibamiya A, Stüdemann T, Köhne M, Bibra CV, Hornaschewitz N, Pecha S, Nejahsie Y, Mannhardt I, Christ T, Reichenspurner H, Hansen A, Klymiuk N, Krane M, Kupatt C, Eschenhagen T, Weinberger F.
Human Engineered Heart Tissue Patches Remuscularize the Injured
Heart in a Dose-Dependent Manner.
Circulation. 2021 May 18;143(20):1991-2006.
https://pubmed.ncbi.nlm.nih.gov/33648345/
Mayr B, Burri M, Vitanova K, Prinzing A, Goppel G, Krane M, Lange R,
Günzinger R.
Serial echocardiographic evaluation of the Perimount Magna Ease
prosthesis.
J Thorac Dis. 2021 Jul;13(7):4104-4113.
https://pubmed.ncbi.nlm.nih.gov/34422340/
Bapat VN, Zaid S, Fukuhara S, Saha S, Vitanova K, Kiefer P, Squiers JJ,
Voisine P, Pirelli L, von Ballmoos MW, Chu MWA, Rodés-Cabau J, DiMaio JM, Borger MA, Lange R, Hagl C, Denti P, Modine T, Kaneko T, Tang GHL; EXPLANT-TAVR Investigators. Surgical Explantation After TAVR Failure: Mid-Term Outcomes From the EXPLANT-TAVR International Registry.
JACC Cardiovasc Interv. 2021 Sep 27;14(18):1978-1991.
https://pubmed.ncbi.nlm.nih.gov/34556271/
Kaneko T, Hirji S, Zaid S, Lange R, Kempfert J, Conradi L, Hagl C, Borger
MA, Taramasso M, Nguyen TC, Ailawadi G, Shah AS, Smith RL, Anselmi A, Romano MA, Ben Ali W, Ramlawi B, Grubb KJ, Robinson NB, Pirelli L, Chu MWA, Andreas M, Obadia JF, Gennari M, Garatti A, Tchetche D, Nazif TM, Bapat VN, Modine T, Denti P, Tang GHL;
CUTTING-EDGE Investigators. Mitral Valve Surgery After Transcatheter Edge-to-Edge Repair: Mid-Term Outcomes From the CUTTING-EDGE
International Registry.
JACC Cardiovasc Interv. 2021 Sep 27;14(18):2010-2021.
https://pubmed.ncbi.nlm.nih.gov/34556275/
Ono M, Burri M, Mayr B, Anderl L, Strbad M, Cleuziou J, Hager A, Hörer J,
Lange R.
Risk Factors for Failed Fontan Procedure After Stage 2 Palliation.
Ann Thorac Surg. 2021 Aug;112(2):610-618.
https://pubmed.ncbi.nlm.nih.gov/32828751/
De Biase C, Siddiqui S, Brochado B, Ziviello F, van Mieghem NM, De Backer O, Sondergaard L, Silveira J, Saint-Etienne C, Bourguignon T, Lange R, Jovanovic M, Berthoumieu P, Bleiziffer S, Tuccillo A, Lemee C, Chapdelaine K, Dumonteil N, Tchetche D.
Contemporary management of severe symptomatic bicuspid aortic valve
stenosis: the BiTri Registry.
J Cardiovasc Med (Hagerstown). 2021 Jun 1;22(6):492-495.
https://pubmed.ncbi.nlm.nih.gov/33136814/
Mazzitelli D, Fischlein T, Rankin JS, Choi YH, Stamm C, Pfeiffer S, Pirk J,
Aboud A, Charitos EI, Fujita B, Stierle U, Reil JC, Voth V, Liebrich M,
Andreas M, Holubec T, Bening C, Albert M, Fila P, Ondrasek J, Murin P, Lange R, Reichenspurner H, Franke U, Gorski A, Moritz A, Laufer G, Hemmer W, Sievers HH, Ensminger S.
Long-Term Outcomes of Patients Undergoing the Ross Procedure.
J Am Coll Cardiol. 2021 Mar 23;77(11):1412-1422.
https://pubmed.ncbi.nlm.nih.gov/33736823/
Barbash IM, Kornowski R, Berkovitch A, Assali A, Erlebach M, Guetta V,
Vaknin Assa H, Lange R, Segev A, Ruge H., Erlebach M, Lange R.
Frequency of Bioprosthetic Valve Fracturing Utilization in an All-Comers Valve-in-Valve TAVR Cohort.
Front Cardiovasc Med. 2021 Jul 1;8:653871.
https://pubmed.ncbi.nlm.nih.gov/34277723/
Ono M, Kido T, Burri M, Anderl L, Ruf B, Cleuziou J, Strbad M, Hager A,
Hörer J, Lange R.
Risk Factors for Thrombus Formation at Stage 2 Palliation and Its Effect on Long-Term Outcome in Patients With Univentricular Heart.
Semin Thorac Cardiovasc Surg. 2021 Mar 7:S1043-0679(21)00104-0.
https://pubmed.ncbi.nlm.nih.gov/33691189/
Pabst von Ohain J, Tonino E, Kaemmerer H, Cleuziou J, Ewert P, Lange R,
Hörer J.
German Heart Centre Munich-45 years of surgery in adults with congenital heart defects: from primary corrections of septal defects and coarctation to complex reoperations.
Cardiovasc Diagn Ther. 2021 Apr;11(2):492-502.
https://pubmed.ncbi.nlm.nih.gov/33968628/
*Krane M, *Dreßen M, *Santamaria G, *My I, *Schneider CM, *Dorn T, *Laue S, Mastantuono E, Berutti R, Rawat H, Gilsbach R, Schneider P, Lahm H, Schwarz S, Doppler SA, Paige S, Puluca N, Doll S, Neb I, Brade T, Zhang Z, Abou-Ajram C, Northoff B, Holdt LM, Sudhop S, Sahara M, Goedel A, Dendorfer A, Tjong FVY, Rijlaarsdam ME, Cleuziou J, Lang N, Kupatt C, Bezzina C, Lange R, Bowles NE, Mann M, Gelb B, Crotti L, Hein L, Meitinger T, Wu S, Sinnecker D, Gruber PJ, Laugwitz K-L, Moretti A.
Sequential defects in cardiac lineage commitment and maturation cause hypoplastic left heart syndrome.
Circulation 2021, accepted